I mean, this thread... There's some useful things here, and some obvious jump-to-conclusions defensive and passive aggressive jabs going on... obviously...
But if you must know, tuning is more skill than it is hardware. I've known people running HPTuners tune their own cars on the streets better than a dyno tuning shop doing it for 20+ years. If you have the aptitude, spend the time, run tests, and have the scientific method down better than just a hunch, I think you (as in anyone) can tune a car. Tuning is the same as racecar drivers: it's 90% tuner; 10% hardware.
Whether you do this with an ECU tune or a piggyback chip won't really matter as much as it seems. There will be advantages to both (for example, the ECU tune is able to manage parameters not normally accessible "externally" via a chip simply altering values, but the chip can be removed with little evidence left behind [though, keep in mind, there is ALWAYS evidence, ALWAYS), but at the end of the day, a finely tuned ECU or chip is capable of "safe" power. One will edge out the other in one area, and another will have abilities the other cannot. I have always found that a skilled tuner is the key. One of my older cars had a canned tune in it from a one-man shop guy that was basically a nobody, but it was LOADS better than the "big company" one that not only had some terrible tuning behaviors, but a terrible support team that instead of trying to fix the tune turned to bullying me into returning it.
Soooo, what I say to this is that it's not what you pick, it's who you're picking it from. Go for an ECU tune, or go for a piggyback. But pick the vendor that seems to be demonstrating actual extensive testing/skill in what they're doing.
Granted, someone might say, "but all of the vendors seem to know what they're doing!" and/or "the car hasn't been out long enough for us to find out who's what!", but I can tell you right now that if you spend the extra time to look closely, you can tell where different vendors' interests lie. They all need to make money, such is the way of business, but the manner in which they present their product says a lot about their view of the car and its owners.
Happy tuning/chipping!