Eh? Air Force One is refueled while in the air, and many other large aircraft intended to stay in the air for extended periods of time are refueled while flying...
Of course, they're DESIGNED to be able to do that and cars are not. Especially considering a CEL is thrown if the gas cap is loose and pressurization isn't achieved when the fuel pump is pulling fuel. Of course, as some people know, this is not immediate: the fuel pump draws so little fuel at a time that it takes about 4-5 miles before the system notices the pressure in the tank isn't right. So for those wondering why it doesn't happen while at idle, the fuel pump is sipping so little fuel during that short span of time that the loss of pressurization isn't outside of normal parameters, yet.